产品名称
Anti-Factor H/CFH Antibody (Clone#OTI5H5)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
ARMD4; ARMS1; CFH; CFHL3; Complement factor H; Factor H; FH; FHL1; H factor 1; HF; HF1; HF2; HUS
免疫原
Human recombinant protein fragment corresponding to amino acids 125-346 of human CFH (NP_001014975) produced in E.coli.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
文献引用格式
Factor H/CFH Antibody (Clone#OTI5H5) (Boster Biological Technology, Wuhan, China. Catalog#M00562-1)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
complement factor H
蛋白名全称
Complement factor H