Anti-AANAT Antibody (Clone#OTI6E1)

50μl/1180 100μl/1960 150μl/2780

AA NAT; AANAT; Serotonin acetylase; Serotonin N acetyltransferase; SNAT

Monoclonal

human

WB

Aanat

OTI6E1

Mouse

IgG1

Human recombinant protein fragment corresponding to amino acids 1-72 of human AANAT (NP_001079) produced in E.coli.

23 kDa

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

500 ug/ml

Liquid

Stable for 12 months from date of receipt. Store at -20°C as received.

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

O88816

AANAT Antibody (Clone#OTI6E1) (Boster Biological Technology, Wuhan, China. Catalog#M03784)

WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC－免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法

arylalkylamine N-acetyltransferase

Serotonin N-acetyltransferase

Western blot (WB):

1:2000