产品名称
Anti-AANAT Antibody (Clone#OTI6E1)
规格/价格
50μl/1180 100μl/1960 150μl/2780
指标别称
AA NAT; AANAT; Serotonin acetylase; Serotonin N acetyltransferase; SNAT
免疫原
Human recombinant protein fragment corresponding to amino acids 1-72 of human AANAT (NP_001079) produced in E.coli.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
文献引用格式
AANAT Antibody (Clone#OTI6E1) (Boster Biological Technology, Wuhan, China. Catalog#M03784)
应用释义
WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC-免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法
基因名全称
arylalkylamine N-acetyltransferase
蛋白名全称
Serotonin N-acetyltransferase