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Anti-uPA/Urokinase/PLAU Antibody (Clone#OTI5H4)

Mouse monoclonal antibody

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筛选器: All IHC WB

M04352-1

  • 50μl ¥1280 150μl ¥2800 100μl ¥2180
  • 货期: 5-7天
  • Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, M04352-1)

    all(5)
  • Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, M04352-1)

    all(5)
  • Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, M04352-1)

    all(5)
  • Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, M04352-1)

    all(5)
  • HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLAU (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLAU (Cat# M04352-1).

    all(5)

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产品名称
Anti-uPA/Urokinase/PLAU Antibody (Clone#OTI5H4)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
ATF; PLAU; U plasminogen activator; uPA; uPA/Urokinase; URK
产品类型
Monoclonal
检验物种
human
应用范围
IHC, WB
基因名称
PLAU
克隆号
OTI5H4
宿主
Mouse
抗体亚型
IgG2a
免疫原
Human recombinant protein fragment corresponding to amino acids 107-379 of human PLAU (NP_002649) produced in E.coli.
计算分子量
49 kDa
实际分子量
46.3 kDa
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度
500 ug/ml
产品形态
Liquid
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Uniprot ID
P00749  
文献引用格式
uPA/Urokinase/PLAU Antibody (Clone#OTI5H4) (Boster Biological Technology, Wuhan, China. Catalog#M04352-1)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
plasminogen activator, urokinase
蛋白名全称
Urokinase-type plasminogen activator
推荐稀释比
Western blot (WB):1:2000
Immunohistochemistry (IHC):1:150

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    Anti-uPA/Urokinase/PLAU Antibody (Clone#OTI5H4)

    筛选器: All IHC WB

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