产品名称
Anti-A2BP1/RBFOX1 Antibody (Clone#OTI1F2)
规格/价格
50μl/1180 100μl/1960 150μl/2780
指标别称
A2BP; A2BP1; ataxin 2 binding protein 1; Fox 1 homolog A; FOX1; HRNBP1; RBFOX1
免疫原
Human recombinant protein fragment corresponding to amino acids 1-210 of human RBFOX1 (NP_061193) produced in E.coli.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
文献引用格式
A2BP1/RBFOX1 Antibody (Clone#OTI1F2) (Boster Biological Technology, Wuhan, China. Catalog#M04462-1)
应用释义
WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC-免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法
基因名全称
RNA binding protein fox-1 homolog 1