Anti-c-Met/MET Antibody

Rabbit polyclonal antibody

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筛选器： All WB

PB0146

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of c-Met/MET using anti-c-Met/MET antibody (PB0146). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat liver tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-c-Met/MET antigen affinity purified polyclonal antibody (PB0146) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for c-Met/MET at approximately 156 kDa. The expected band size for c-Met/MET is at 156 kDa.
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产品名称

Anti-c-Met/MET Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

AUTS9; c-Met; c-Met (Cytoplasmic); HGF receptor; HGF/SF receptor; HGFR; MET; Proto oncogene c Met; RCCP2; Scatter factor receptor; SF receptor; Tyrosine protein kinase Met

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

基因名称

MET

宿主

Rabbit

抗体亚型

IgG

免疫原

E.coli-derived human Met recombinant protein (Position: D208-S407). Human Met shares 90% and 91% amino acid (aa) sequences identity with mouse and rat Met, respectively.

计算分子量

156 kDa

实际分子量

156 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

c-Met, also called MET and hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. It is mapped to 7q31.2. The protein possesses tyrosine kinase activity. MET is a membrane receptor that is essential for embryonic development and wound healing. It induces several biological responses that collectively give rise to a program known as invasive growth. MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability of normal stem cells to express MET, and thus become the cause of cancer persistence and spread to other sites in the body.

Uniprot ID

P08581

文献引用格式

c-Met/MET Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB0146)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

MET proto-oncogene, receptor tyrosine kinase

蛋白名全称

Hepatocyte growth factor receptor

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实验步骤

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