Anti-HIF-1 alpha/HIF1A Antibody (Clone#17H18)

Rabbit monoclonal antibody

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筛选器： All WB IHC ICC/IF

BM4083

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of HIF-1 alpha expression in Ramos cell lysate.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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Immunohistochemical analysis of paraffin-embedded human kindey, using HIF-1 alpha Antibody.
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Immunofluorescent analysis of Hela cells, using HIF-1 alpha Antibody.
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产品简介>

产品名称

Anti-HIF-1 alpha/HIF1A Antibody (Clone#17H18)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

ARNT interacting protein; bHLHe78; HIF 1 alpha; HIF 1alpha; HIF1; HIF-1; HIF1 ALPHA; HIF1A; HIF-1α; Member of PAS protein 1; MOP1; PASD8

产品类型

Monoclonal

检验物种

human

应用范围

WB,IHC,ICC/IF

基因名称

HIF1A

克隆号

17H18

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human HIF-1 alpha

计算分子量

93 kDa

实际分子量

120 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.

Uniprot ID

Q16665

文献引用格式

HIF-1 alpha/HIF1A Antibody (Clone#17H18) (Boster Biological Technology, Wuhan, China. Catalog#BM4083)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

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