Anti-SIRT1 (Phospho-S47) Antibody (Clone#FDA-19)

Rabbit Monoclonal antibody

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筛选器： All WB IHC ICC/IF

BM4507

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of Phospho-SIRT1 (S47) expression in (1) HEK293 cell lysate; (2) HEK293 cell lysate treated with LP.
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Immunohistochemical analysis of paraffin-embedded human colon, using Phospho-SIRT1 (S47) Antibody.
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产品简介>

产品名称

Anti-SIRT1 (Phospho-S47) Antibody (Clone#FDA-19)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

hSIR2; hSIRT1; SIR2 like protein 1; SIR2L1; SIRT1

产品类型

Monoclonal

检验物种

human

应用范围

WB, IHC, ICC/IF

基因名称

SIRT1

克隆号

FDA-19

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Phospho-SIRT1 (S47)

计算分子量

82 kDa

实际分子量

110-120 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Sirtuin 1, also known as SIR2L1 or SIRT1, is a protein that in humans is encoded by the SIRT1 gene. It is mapped to 10q21.3. Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. Sirtuin 1 is downregulated in cells that have high insulin resistance and inducing its expression increases insulin sensitivity, suggesting the molecule is associated with improving insulin sensitivity. Furthermore, Sirtuin 1 was shown to de-acetylate and affect the activity of both members of the PGC1-alpha/ERR-alpha complex, which are essential metabolic regulatory transcription factors.

Uniprot ID

Q96EB6

文献引用格式

SIRT1 (Phospho-S47) Antibody (Clone#FDA-19) (Boster Biological Technology, Wuhan, China. Catalog#BM4507)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

NAD-dependent protein deacetylase sirtuin-1

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