产品名称
Anti-ABCC1 Antibody (Clone#ABFD-1)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
ABC29; ABCC; ABCC1; Leukotriene C(4) transporter; LTC4 transporter; MRP; MRP1
免疫原
A synthesized peptide derived from human MRP1
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
文献引用格式
ABCC1 Antibody (Clone#ABFD-1) (Boster Biological Technology, Wuhan, China. Catalog#BM5146)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Multidrug resistance-associated protein 1
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| Flow Cytometry (FCM): | 1:20 |
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