Human p75NTR/NGFR ELISA Kit

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EK0972

96T ￥2480
货期：现货

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Human TNFRSF16/NGFR ELISA Kit standard curve
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产品简介>

产品名称

Human p75NTR/NGFR ELISA Kit

规格/价格

96T/2480

指标别名

CD271; Gp80 LNGFR; NGF receptor; NGFR; p75; p75 ICD; p75(NTR); p75NTR; TNFRSF16

免疫原

sf21, K29-N250

交叉反应

There is no detectable cross-reactivity with other relevant proteins.

检测范围

62.5 pg/ml - 4000 pg/ml

基因名称

NGFR

基因名全称

nerve growth factor receptor

Uniprot ID

P08138

文献引用格式

Human p75NTR/NGFR ELISA Kit (Boster Biological Technology, Wuhan, China. Catalog#EK0972)

背景资料

Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) because of its ability to bind at low affinity not only to NGF, but also other neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5. The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. The neurotrophin receptor p75(NTR), a tumor necrosis factor receptor superfamily member expressed in hepatic stellate cells after fibrotic and cirrhotic liver injury in humans, is a regulator of liver repair. In mice, depletion of p75(NTR) exacerbated liver pathology and inhibited hepatocyte proliferation in vivo. In addition, it is showed that neurotrophins activate p75(NTR) to induce apoptosis through the induction of the sphingomyelin (SM) cycle and increased production of ceramide. Overexpression of p75(NTR) is also found to activate the SM pathway.

显色时间

25-30分钟

试剂盒内容

Catalog number	Description	Quantity
EK0972-CAP	96-well plate precoated with anti- human TNFRSF16 antibody	1
EK0972-ST	Lyophilized recombinant human TNFRSF16 standard	10ng/tube×2
EK0972-DA	Biotinylated anti- human TNFRSF16 antibody	100μl(dilution 1:100)
AR1103	Avidin-Biotin-Peroxidase Complex (ABC)	100μl(dilution 1:100)
AR1106-1	Sample diluent buffer	30 ml
AR1106-2	Antibody diluent buffer	12ml
AR1106-3	ABC diluent buffer	12ml
AR1104	TMB color developing agent	10ml
AR1105	TMB stop solution	10ml
PLA-SEA	Adhesive cover	4

批内差/批间差

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	16	16	16	24	24	24
Mean(pg/ml)	194	811	1003	200	784	959
Standard deviation	11.44	46.22	52.15	12.6	46.25	53.7
CV(%)	5.9	5.7	5.2	6.3	5.9	5.6

典型数据示例

Concentration(pg/ml)	0	62.5	125	250	500	1000	2000	4000
O.D.	0.009	0.057	0.129	0.205	0.416	0.685	1.375	2.203

保存条件与有效期

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Human p75NTR/NGFR ELISA Kit

EK0972

产品简介>

产品名称

规格/价格

指标别名

免疫原

交叉反应

检测范围

基因名称

基因名全称

Uniprot ID

文献引用格式

背景资料

显色时间

试剂盒内容

批内差/批间差

典型数据示例

保存条件与有效期

应用范围

检验物种

检测方法

样本类型

实验时长

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Human p75NTR/NGFR ELISA Kit

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