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Mouse p75NTR/NGFR ELISA Kit

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EK2126

  • 96T ¥2480
  • 货期: 现货

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产品名称
Mouse p75NTR/NGFR ELISA Kit
规格/价格
96T/2480
指标别名
CD271; Gp80 LNGFR; NGF receptor; NGFR; p75; p75 ICD; p75(NTR); p75NTR; TNFRSF16
免疫原
Expression system for standard: NS0; Immunogen sequence: K22-P246
交叉反应
There is no detectable cross-reactivity with other relevant proteins.
检测范围
31.2pg/ml-2000pg/ml
基因名称
Ngfr
基因名全称
nerve growth factor receptor (TNFR superfamily, member 16)
Uniprot ID
Q9Z0W1  
文献引用格式
Mouse p75NTR/NGFR ELISA Kit (Boster Biological Technology, Wuhan, China. Catalog#EK2126)
背景资料
Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) because of its ability to bind at low affinity not only to NGF, but also other neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5. The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. The neurotrophin receptor p75(NTR), a tumor necrosis factor receptor superfamily member expressed in hepatic stellate cells after fibrotic and cirrhotic liver injury in humans, is a regulator of liver repair. In mice, depletion of p75(NTR) exacerbated liver pathology and inhibited hepatocyte proliferation in vivo. In addition, it is showed that neurotrophins activate p75(NTR) to induce apoptosis through the induction of the sphingomyelin (SM) cycle and increased production of ceramide. Overexpression of p75(NTR) is also found to activate the SM pathway.
显色时间
15-20分钟
试剂盒内容
Catalog numberDescriptionQuantity
EK2126-CAP96-well plate precoated with anti- Mouse NGFR/TNFRSF16 A antibody1
EK2126-STLyophilized recombinant Mouse NGFR/TNFRSF16 A standard10ng/tube×2
EK2126 -DABiotinylated anti- Mouse NGFR/TNFRSF16 A antibody100μl(dilution 1:100)
AR1103Avidin-Biotin-Peroxidase Complex (ABC)100μl(dilution 1:100)
AR1106-1Sample diluent buffer30ml
AR1106-2Antibody diluent buffer12ml
AR1106-3ABC diluent buffer12ml
AR1104TMB color developing agent10ml
AR1105TMB stop solution10ml
PLA-SEAAdhesive cover4
批内差/批间差
Intra-Assay Precision
Inter-Assay Precision
Sample123123
n161616242424
Mean(pg/ml)5529984161263907
Standard deviation4.0720.6347.104.3320.7876.19
CV(%)7.4%6.9%5.6%7.1%7.9%8.4%
典型数据示例
Concentration(pg/ml)031.262.512525050010002000
O.D.0.0330.1240.1610.2530.4370.7681.4531.923
保存条件与有效期
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
应用范围
ELISA
检验物种
mouse
检测方法
酶联免疫双抗夹心法
样本类型
Cell Culture Supernatants, Serum, Plasma (heparin, EDTA) and Saliva
实验时长
3.5h

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