Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)

Mouse monoclonal antibody

说明书一键复制产品信息

筛选器： All WB

M00366-3

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

加入购物车立即购买

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA.
all(1)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

platelet derived growth factor receptor alpha; CD140A; PDGFR-2; PDGFR2; PDGFRA

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

基因名称

PDGFRA

克隆号

OTI2B12

宿主

Mouse

抗体亚型

IgG1

免疫原

Human recombinant protein fragment corresponding to amino acids 32-324 of human PDGFRA (NP_006197) produced in E.coli.

计算分子量

123 kDa

实际分子量

120.3 kDa

成分

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

纯化方式

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

浓度

500 ug/ml

产品形态

Liquid

保存条件

Stable for 12 months from date of receipt. Store at -20°C as received.

背景资料

PDGFRA(Platelet-derived growth factor receptor, alpha), also called PDGFR2, encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. The PDGFA gene is mapped on 4q12. The PDGFRA-FIP1L1 gene is a constitutively activated tyrosine kinase that transforms hematopoietic cells and is a therapeutic target of imatinib. The PDGFRA gene contains 23 exons spanning about 65 kb. Using the human PDGFRA promoter linked to a luciferase reporter, Joosten et al. showed that PAX1 acts as a transcriptional activator of the PDGFRA gene in differentiated human embryonal carcinoma cells. PDGFRA is responsible for mediating cellular contraction of multiple growth factors: TGFB1 and members of the PDGF family. Lei et al. noted that in the rabbit model of the disease, PDGFRA is dramatically more capable of promoting PVR than is the closely related PDGFRB. PDGFRA is a critical receptor required for human CMV infection, and thus a target for novel antiviral therapies.

Uniprot ID

P16234

文献引用格式

PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12) (Boster Biological Technology, Wuhan, China. Catalog#M00366-3)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)

筛选器： All WB

M00366-3

产品简介>

产品名称

规格/价格

指标别称

产品类型

检验物种

应用范围

基因名称

克隆号

宿主

抗体亚型

免疫原

计算分子量

实际分子量

成分

纯化方式

浓度

产品形态

保存条件

背景资料

Uniprot ID

文献引用格式

应用释义

基因名全称

蛋白名全称

推荐稀释比

实验方案>

引用文献(0)>

All All Species 清除

相关产品>

A00366

BM4982

PB0822

成功添加到购物车

Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)

筛选器： All WB

产品中心

技术服务

技术资源

最新活动

关于BOSTER

联系订购

联系我们

关注我们

点击下列客服在线咨询：

清除