Anti-TGFBR2 Antibody

Rabbit polyclonal antibody

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筛选器： All WB

PB0873

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of TGFBR2 using anti-TGFBR2 antibody (PB0873). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human HepG2 whole cell lysates,
Lane 2: human A549 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-TGFBR2 antigen affinity purified polyclonal antibody (PB0873) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for TGFBR2 at approximately 70 kDa. The expected band size for TGFBR2 is at 65 kDa.
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产品名称

Anti-TGFBR2 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFbeta RII; TGFBR2; TGFR 2

产品类型

Polyclonal

检验物种

human

应用范围

基因名称

TGFBR2

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR2 different from the related mouse sequence by five amino acids, and from the related rat sequence by eight amino acids.

计算分子量

65 kDa

实际分子量

70 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

TGFBR2 (transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encodes a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been characterized.

Uniprot ID

P37173

文献引用格式

TGFBR2 Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB0873)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

transforming growth factor, beta receptor II (70/80kDa)

蛋白名全称

TGF-beta receptor type-2

实验方案>

实验步骤

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