Anti-Caspase 1/CASP1 (p20) Antibody

Rabbit polyclonal antibody

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筛选器： All WB

BA2220

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of Caspase 1/CASP1 (p20) using anti-Caspase 1/CASP1 (p20) antibody (BA2220). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat thymus tissue lysates,
Lane 2: rat C6 whole cell lysates,
Lane 3: mouse thymus tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-Caspase 1/CASP1 (p20) antigen affinity purified polyclonal antibody (BA2220) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for Caspase 1/CASP1 (p20) at approximately 46 kDa. The expected band size for Caspase 1/CASP1 (p20) is at 46 kDa.
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产品名称

Anti-Caspase 1/CASP1 (p20) Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

CASP 1; CASP1; Caspase 1; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL1BC; IL1BCE; p10; p20; P45

产品类型

Polyclonal

检验物种

mouse, rat

应用范围

基因名称

CASP1

宿主

Rabbit

抗体亚型

IgG

免疫原

Polypeptide

计算分子量

46 kDa

实际分子量

46 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Uniprot ID

P29452

RRID

AB_2819011

文献引用格式

Caspase 1/CASP1 (p20) Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA2220)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Caspase-1

实验方案>

实验步骤

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