Anti-ATM (Phospho-S1981) Antibody (Clone#AEE-1)

Rabbit Monoclonal antibody

说明书

筛选器： All WB IHC ICC/IF IP

BM4008

50μl ￥1180 100μl ￥1960 150μl ￥2780
货期：现货

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Western blot analysis of Phospho-ATM (Ser1981) in (1) HEK293 cell lysate; (2) HEK293 cell lysate treated with Doxorubicin.
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Immunohistochemical analysis of paraffin-embedded human liver, using Phospho-ATM (S1981) Antibody.
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产品简介>

产品名称

Anti-ATM (Phospho-S1981) Antibody (Clone#AEE-1)

规格/价格

50μl/1180 100μl/1960 150μl/2780

指标别称

A T mutated; AT1; ATA; ataxia telangiectasia mutated; ATC; ATD; ATDC; ATE; ATM; Serine protein kinase ATM; TEL1; TELO1

产品类型

Monoclonal

检验物种

human, mouse

应用范围

WB, IHC, ICC/IF, IP

基因名称

ATM

克隆号

AEE-1

抗体来源

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Phospho-ATM (S1981)

计算分子量

351 kDa

实际分子量

350 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

ATM(ataxia telangiectasia mutated), also known as TEL1 or TELO1, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. The ATM gene is mapped to chromosome 11q22.3. ATM has an essential role in the reconstitutive capacity of hematopoietic stem cells but is not as important for the proliferation or differentiation of progenitors in a telomere-independent manner. ATM functions directly in the repair of chromosomal DNA double-stranded breaks by maintaining DNA ends in repair complexes generated during lymphocyte gene assembly.

Uniprot ID

Q13315

文献引用格式

ATM (Phospho-S1981) Antibody (Clone#AEE-1) (Boster Biological Technology, Wuhan, China. Catalog#BM4008)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光; ICC－免疫细胞化学; IHC-F- 冰冻切片免疫组化; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Serine-protein kinase ATM

实验方案>

实验步骤

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