产品名称
Human TIMP3 Quick ELISA Kit
指标别名
HSMRK222; K222; K222TA2; Metalloproteinase inhibitor 3; Protein MIG 5; SFD; Timp 3; TIMP3; TIMP-3
免疫原
Expression system for standard: NS0; Immunogen sequence: C24-P211
交叉反应
There is no detectable cross-reactivity with other relevant proteins.
基因名全称
TIMP metallopeptidase inhibitor 3
文献引用格式
Human TIMP3 Quick ELISA Kit (Boster Biological Technology, Wuhan, China. Catalog#FEK0523)
背景资料
The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).
试剂盒内容
Catalog number | Description | Quantity |
FEK0523-CAP | Anti-human TIMP-3 Pre-coated 96-well Strip Microplate | 1 |
FEK0523-ST | human TIMP-3 standard | 10ng/tube×2 |
FEK0523-H | HRP Linked Anti-human TIMP-3 Antibody | 6ml |
AR1106-1 | Sample diluent buffer | 15ml |
AR1106-7 | TBS-T Wash Buffer (25x) | 12ml |
AR1104 | TMB color developing agent | 10ml |
AR1105 | Stop solution | 10ml |
PLA-SEA | Adhesive cover | 2 |
批内差/批间差
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 16 | 16 | 16 | 24 | 24 | 24 |
Mean(pg/ml) | 233 | 1357 | 4383 | 248 | 1474 | 4049 |
Standard deviation | 16.31 | 92.27 | 271.74 | 21.08 | 120.86 | 327.96 |
CV(%) | 7% | 6.8% | 6.2% | 8.5% | 8.2% | 8.1% |
典型数据示例
Concentration(pg/ml) | 0 | 156 | 312 | 625 | 1250 | 2500 | 5000 | 10000 |
O.D. | 0.111 | 0.160 | 0.190 | 0.231 | 0.414 | 0.803 | 1.767 | 2.388 |
保存条件与有效期
Store at 4℃ for 6 months.
样本类型
Cell Culture Supernatants, Serum, Plasma (heparin, EDTA) and Saliva