产品名称
Human IP10/CXCL10 Quick ELISA Kit
指标别名
C X C motif chemokine 10; C7; crg 2; CXCL10; CXCL10/IP10; Gamma IP10; gIP 10; IFI10; INP10; IP 10; IP10; mob 1; SCYB10; Small inducible cytokine B10
免疫原
Expression system for standard: E.coli; Immunogen sequence: V22-P98
交叉反应
There is no detectable cross-reactivity with other relevant proteins.
基因名全称
chemokine (C-X-C motif) ligand 10
文献引用格式
Human IP10/CXCL10 Quick ELISA Kit (Boster Biological Technology, Wuhan, China. Catalog#FEK0735)
背景资料
Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
试剂盒内容
| Catalog number | Description | Quantity |
| FEK0735-CAP | Anti-Pre-coated 96-well Strip Microplate | 1 |
| FEK0735-ST | Human CXCL10 standard | 10ng/tube×2 |
| FEK0735-A | Human CXCL10 Antibody A | 3ml |
| FEK0735-B | Human CXCL10 Antibody B | 3ml |
| AR1106-1 | Sample diluent buffer | 15ml |
| AR1106-7 | TBS-T Wash Buffer (25x) | 12ml |
| AR1104 | TMB color developing agent | 10ml |
| AR1105 | Stop solution | 10ml |
| PLA-SEA | Adhesive cover | 2 |
批内差/批间差
| Sample | 1 | 2 | 3 | 1 | 2 | 3 |
| n | 16 | 16 | 16 | 24 | 24 | 24 |
| Mean(pg/ml) | 60 | 243 | 879 | 64 | 223 | 865 |
| Standard deviation | 3.24 | 19.19 | 45.7 | 4.28 | 19.4 | 47.57 |
| CV(%) | 5.4% | 7.9% | 5.2% | 6.7% | 8.7% | 5.5% |
典型数据示例
| Concentration(pg/ml) | 0 | 31.2 | 62.5 | 125 | 250 | 500 | 1000 | 2000 |
| O.D. | 0.025 | 0.094 | 0.145 | 0.252 | 0.430 | 0.759 | 1.388 | 2.144 |
保存条件与有效期
Store at 4℃ for 6 months.
样本类型
Cell Culture Supernatants, Serum, Plasma (heparin, EDTA), Saliva and Urine
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