产品名称
Anti-AMPK Alpha 1/PRKAA1 (Phospho-T183)/AMPK Alpha 2/PRKAA2 (Phospho-T172) Antibody (Clone#31P05)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
AMPK; AMPK alpha; AMPK alpha 1; AMPK subunit alpha 1; AMPK1; AMPKa1; PRKAA1; AMPK alpha 2; AMPK subunit alpha 2; AMPK2; AMPKa2; PRKAA2
免疫原
Synthetic phosphopeptide corresponding to residues surrounding Thr183 of human AMPK alpha 1.
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Protein A affinity purified.
保存条件
12 months from date of receipt,-20℃ as supplied.
背景资料
5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
文献引用格式
AMPK Alpha 1/PRKAA1 (Phospho-T183)/AMPK Alpha 2/PRKAA2 (Phospho-T172) Antibody (Clone#31P05) (Boster Biological Technology, Wuhan, China. Catalog#M00994-3)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
aldehyde dehydrogenase 6 family member A1/aldehyde dehydrogenase 6 family member A2
蛋白名全称
5'-AMP-activated protein kinase catalytic subunit alpha-1/5'-AMP-activated protein kinase catalytic subunit alpha-2
推荐稀释比
Western blot (WB): | 1:500-2000 |
Immunohistochemistry (IHC): | 1:50-200 |