Anti-IL-1 beta/IL1B Antibody (Clone#OTI1A7)

Mouse monoclonal antibody

说明书

筛选器： All WB

M00101-4

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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Figure 1. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.
all(1)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-IL-1 beta/IL1B Antibody (Clone#OTI1A7)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

IL1 beta; Catabolin; IL 1; IL 1 beta; IL1 BETA; IL-1 beta; IL1- beta; IL1B; IL1beta; IL1F2; IL-1β; Interleukin 1 beta; interleukin 1; beta; Pro IL-1β; IL 1B; IL-1B

产品类型

Monoclonal

检验物种

human

应用范围

基因名称

IL1B

克隆号

OTI1A7

抗体来源

Mouse

抗体亚型

IgG1

免疫原

Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.

计算分子量

31 kDa

实际分子量

30.6 kDa

成分

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

纯化方式

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

浓度

500 ug/ml

产品形态

Liquid

保存条件

Stable for 12 months from date of receipt. Store at -20°C as received.

背景资料

Interleukin-1β (IL-1β) is a potent stimulator of bone resorption whose gene is mapped to 2q14, and has been implicated in the pathogenesis of high bone turnover and osteoporosis. IL-1β, a prominent microglia-derived cytokine, caused oligodendrocyte death in coculture with astrocytes and microglia, but not in pure culture of oligodendrocytes alone. It also can cause nuclear export of a specific NCOR corepressor complex, resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes. Furthermore, Microenvironmental IL-1β and, to a lesser extent, IL-1α are required for in vivo angiogenesis and invasiveness of different tumor cells. Additional, the cooperation of IL-1β and PDGFB induces contractile-to-synthetic phenotype modulation of human aortic smooth muscle cells in culture. Moreover, the association with disease may be explained by the biologic properties of IL-1β, which is an important proinflammatory cytokine and a powerful inhibitor of gastric acid secretion.

Uniprot ID

P10749

文献引用格式

IL-1 beta/IL1B Antibody (Clone#OTI1A7) (Boster Biological Technology, Wuhan, China. Catalog#M00101-4)

应用释义

WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC－免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法

Anti-IL-1 beta/IL1B Antibody (Clone#OTI1A7)

筛选器： All WB

M00101-4

产品简介>

产品名称

规格/价格

指标别称

产品类型

检验物种

应用范围

基因名称

克隆号

抗体来源

抗体亚型

免疫原

计算分子量

实际分子量

成分

纯化方式

浓度

产品形态

保存条件

背景资料

Uniprot ID

文献引用格式

应用释义

基因名全称

蛋白名全称

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实验方案>

引用文献(0)>

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Anti-IL-1 beta/IL1B Antibody (Clone#OTI1A7)

筛选器： All WB

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