Anti-P glycoprotein/ABCB1 Antibody (Clone#FDB-1)

Rabbit monoclonal antibody

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筛选器： All WB IHC

BM4508

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of P Glycoprotein expression in HeLa cell lysate.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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IHC analysis of P glycoprotein/ABCB1 using anti-P glycoprotein/ABCB1 antibody (BM4508) .
P glycoprotein/ABCB1 was detected in a paraffin-embedded section of human cardiac muscle tissue. The tissue section was incubated with rabbit anti-P glycoprotein/ABCB1 Antibody (BM4508) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.
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产品名称

Anti-P glycoprotein/ABCB1 Antibody (Clone#FDB-1)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

ABC20; ABCB1; CD243; CLCS; GP170; MDR1; Multidrug resistance protein 1; P glycoprotein; P glycoprotein 1; P-gp

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IHC

基因名称

ABCB1

克隆号

FDB-1

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human P Glycoprotein

计算分子量

141 kDa

实际分子量

130-180 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

P-GP, also called ABCB1 or PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier.

Uniprot ID

P08183

文献引用格式

P glycoprotein/ABCB1 Antibody (Clone#FDB-1) (Boster Biological Technology, Wuhan, China. Catalog#BM4508)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Multidrug resistance protein 1

实验方案>

实验步骤

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