Anti-PAK1/2/3 (Phospho-S144+S141+S139) Antibody (Clone#CFF-16)

Rabbit Monoclonal antibody

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筛选器： All WB IHC ICC/IF IP FCM

BM4224

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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Western blot analysis of Phospho-PAK1/2/3 expression in HeLa Cell lysate treated with lambda phosphatase.
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Immunohistochemical analysis of paraffin-embedded mouse brain, using Phospho-PAK1/2/3 (S144+S141+S139) Antibody.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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All lanes use the Antibody for 1 hour at room temperature.
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产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-PAK1/2/3 (Phospho-S144+S141+S139) Antibody (Clone#CFF-16)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

ADRB2; Alpha-PAK; CDC42/RAC effector kinase PAK-A; EC 2.7.11.1; P65-PAK; P68-PAK; PAK1 (phospho S144); PAK2 (phospho S141); PAK3 (phospho S139)

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IHC, ICC/IF, IP, FCM

基因名称

PAK1/PAK2/PAK3

克隆号

CFF-16

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Phospho-PAK1/2/3 (S144+S141+S139)

实际分子量

65 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Serine/threonine-protein kinase PAK 3 is an enzyme that in humans is encoded by the PAK3 gene. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

Uniprot ID

Q13153/Q13177/O75914

文献引用格式

PAK1/2/3 (Phospho-S144+S141+S139) Antibody (Clone#CFF-16) (Boster Biological Technology, Wuhan, China. Catalog#BM4224)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Serine/threonine-protein kinase PAK 3

实验方案>

实验步骤

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