Anti-ERCC6 Antibody

Rabbit polyclonal antibody

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筛选器： All WB

PB1109

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of ERCC6 using anti-ERCC6 antibody (PB1109). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat liver tissue lysates,
Lane 2: human COLO320 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-ERCC6 antigen affinity purified polyclonal antibody (PB1109) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for ERCC6 at approximately 168 kDa. The expected band size for ERCC6 is at 168 kDa.
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产品简介>

产品名称

Anti-ERCC6 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

ARMD5; ATP dependent helicase ERCC6; CKN2; Cockayne syndrome protein CSB; COFS; COFS1; CSB; ERCC6; ERCC6/CSB; RAD26

产品类型

Polyclonal

检验物种

human

应用范围

基因名称

ERCC6

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human CSB

计算分子量

168 kDa

实际分子量

168 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

Uniprot ID

Q03468

文献引用格式

ERCC6 Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB1109)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

ERCC excision repair 6, chromatin remodeling factor

蛋白名全称

DNA excision repair protein ERCC-6

实验方案>

实验步骤

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