产品名称
Anti-CD163 DyLight 488 Conjugated Antibody
指标别称
CD163; CD163 molecule; Hemoglobin scavenger receptor; M130; MM130; sCD163
免疫原
E. coli-derived human CD163 recombinant protein (Position: T47-E201).
激发/发射光谱
Amax=488nm; Emax=515-545nm
成分
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
纯化方式
Immunogen affinity purified.
保存条件
At -20˚C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
背景资料
CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
文献引用格式
CD163 DyLight 488 Conjugated Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00812-Dyl488)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
推荐配套的二抗和检测试剂
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。
推荐稀释比
Flow cytometry (FCM): | 1-3 μg/1x106 cells |