Anti-CYP2A6 Antibody

Rabbit polyclonal antibody

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筛选器： All WB

A00947-2

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of CYP2A6 using anti-CYP2A6 antibody (A00947-2). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat RH35 whole cell lysates,
Lane 2: mouse HEPA1-6 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-CYP2A6 antigen affinity purified polyclonal antibody (A00947-2) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for CYP2A6 at approximately 57 kDa. The expected band size for CYP2A6 is at 57 kDa.
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产品名称

Anti-CYP2A6 Antibody

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

Coumarin 7 hydroxylase; CYP2A; CYP2A3; CYP2A6; CYPIIA6; Cytochrome P450 2A6; Cytochrome P450 IIA3; Cytochrome P450(I); P450C2A; P450PB

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

基因名称

CYP2A6

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Cytochrome P450 2A6/CYP2A6.

计算分子量

57 kDa

实际分子量

57 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Cytochrome P450 2A6 (abbreviated°CYP2A6) is a member of the°Cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. CYP2A6 is the primary enzyme responsible for the oxidation of nicotine and°Cotinine. It is also involved in the metabolism of several pharmaceuticals, carcinogens, and a number of coumarin-type alkaloids. CYP2A6 is the only enzyme in the human body that appreciably catalyzes the 7-hydroxylation of°Coumarin, such that the formation of the product of this reaction, 7-hydroxycoumarin, is used as a probe for CYP2A6 activity. The CYP2A6 gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.

Uniprot ID

P11509

文献引用格式

CYP2A6 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00947-2)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

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