Anti-BMPR1B Antibody

Rabbit polyclonal antibody

说明书一键复制产品信息

筛选器： All WB

BA3305

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

加入购物车立即购买

Western blot analysis of BMPR1B using anti-BMPR1B antibody (BA3305).
Lane 1: recombinant Human BMPR1B Protein 10ng,
Lane 2: recombinant Human BMPR1B Protein 5ng,
Lane 3: recombinant Human BMPR1B Protein 2.5ng,
Lane 4: recombinant Human BMPR1B Protein 1.25ng.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-BMPR1B antigen affinity purified polyclonal antibody (BA3305) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for BMPR1B at approximately 49 kDa.
all(1)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-BMPR1B Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

bone morphogenetic protein receptor type 1B; ALK-6; ALK6; AMDD; BDA1D; BDA2; CDw293; BMPR1B

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

基因名称

BMPR1B

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human BMPR1B, different from the related rat and mouse sequences by one amino acid.

计算分子量

57 kDa

实际分子量

57 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

BMPR1B(Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein(BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine(threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al.(1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al.(1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Uniprot ID

O00238

文献引用格式

BMPR1B Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA3305)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

bone morphogenetic protein receptor, type IB

蛋白名全称

Bone morphogenetic protein receptor type-1B

实验方案>

实验步骤

引用文献(0)>

清除