Anti-BMPR1B Antibody

Rabbit polyclonal antibody

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筛选器： All WB IHC

PB9528

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of BMPR1B using anti-BMPR1B antibody (PB9528). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human placenta tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-BMPR1B antigen affinity purified polyclonal antibody (PB9528) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for BMPR1B at approximately 57 kDa. The expected band size for BMPR1B is at 57 kDa.
all(2)
IHC analysis of BMPR1B using anti-BMPR1B antibody (PB9528).
BMPR1B was detected in a paraffin-embedded section of human prostatic cancer tissue. Biotinylated goat anti-rabbit IgG was used as secondary antibody. The tissue section was incubated with rabbit anti-BMPR1B Antibody (PB9528) at a dilution of 1:200 and developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB (Catalog # AR1027) as the chromogen.
all(2)

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产品简介>

产品名称

Anti-BMPR1B Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

bone morphogenetic protein receptor type 1B; ALK-6; ALK6; AMDD; BDA1D; BDA2; CDw293; BMPR1B

产品类型

Polyclonal

检验物种

human

应用范围

WB, IHC

基因名称

BMPR1B

宿主

Rabbit

抗体亚型

IgG

免疫原

E.coli-derived human BMPR1B recombinant protein (Position: K14-Q184). Human BMPR1B shares 97.1% amino acid (aa) sequence identity with mouse BMPR1B.

计算分子量

57 kDa

实际分子量

57 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

BMPR1B (Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al. (1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al. (1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Uniprot ID

O00238

文献引用格式

BMPR1B Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB9528)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

bone morphogenetic protein receptor, type IB

蛋白名全称

Bone morphogenetic protein receptor type-1B

实验方案>

实验步骤

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