Anti-Beta Amyloid/APP Antibody (Clone#BGC-1)

Rabbit monoclonal antibody

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筛选器： All WB IP IHC ICC/IF FCM

BM4128

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of anti-Beta Amyloid/APP antibody (BM4128). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat brain tissue lysates,
Lane 2: mouse brain tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-Beta Amyloid/APP antigen affinity purified monoclonal antibody (BM4128) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for Beta Amyloid/APP at approximately 100 kDa. The expected band size for Beta Amyloid/APP is at 87 kDa.
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Immunoprecipitate (IP) analysis using the Antibody. (wb)
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Immunohistochemical analysis of paraffin-embedded human brain, using Amyloid beta A4 Antibody .
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Immunofluorescent analysis of SH-SY5Y cells, using Amyloid beta A4 Antibody .
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产品名称

Anti-Beta Amyloid/APP Antibody (Clone#BGC-1)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

ABETA; ABPP; amyloid beta 1-42; Amyloid beta A4 protein; amyloid P; amyloid precursor protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; APP; APPI; Aβ1-42; beta Amyloid

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IP, IHC, ICC/IF, FCM

基因名称

APP

克隆号

BGC-1

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Amyloid beta A4

计算分子量

87 kDa

实际分子量

100 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

beta Amyloid, also called Abeta or Abeta, denotes peptides of 36–43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

Uniprot ID

P05067

文献引用格式

Beta Amyloid/APP Antibody (Clone#BGC-1) (Boster Biological Technology, Wuhan, China. Catalog#BM4128)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Amyloid beta A4 protein

实验方案>

实验步骤

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