Anti-MMP8 Antibody (Clone#EFA-13)

Rabbit monoclonal antibody

说明书一键复制产品信息

筛选器： All WB IHC ICC/IF IP FCM

BM4427

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

加入购物车立即购买

Western blot analysis of MMP8 expression in Human placenta lysate.
all(6)
IHC analysis of MMP8 using anti-MMP8 antibody (BM4427).
MMP8 was detected in a paraffin-embedded section of human spleen tissue. The tissue section was incubated with rabbit anti-MMP8 Antibody (BM4427) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.
all(6)
IHC analysis of MMP8 using anti-MMP8 antibody (BM4427).
MMP8 was detected in a paraffin-embedded section of mouse spleen tissue. The tissue section was incubated with rabbit anti-MMP8 Antibody (BM4427) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.
all(6)
all(6)
all(6)
all(6)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-MMP8 Antibody (Clone#EFA-13)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

CLG1; HNC; Matrix metalloproteinase 8; MMP 8; MMP8; Neutrophil collagenase; PMNL CL; PMNL collagenase

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IHC, ICC/IF, IP, FCM

基因名称

MMP8

克隆号

EFA-13

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human MMP8

计算分子量

53 kDa

实际分子量

53 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

MMP8 (Matrix metalloproteinase 8) is a member of the family of matrix metalloproteinases. It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity. MMP8 is mapped to 11q21-q22. MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The enzyme exhibits 58% homology to human fibroblast collagenase and has the same domain structure. It consists of a 20-residue signal peptide, and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond. MMP8 was found to possess 57% identity with the deduced protein sequence for fibroblast collagenase with 72% chemical similarity. Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression, but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer. MMP8 has a paradoxical protective role in cancer and provides a genetic model to evaluate the molecular basis of gender differences in cancer susceptibility.

Uniprot ID

P22894

文献引用格式

MMP8 Antibody (Clone#EFA-13) (Boster Biological Technology, Wuhan, China. Catalog#BM4427)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Neutrophil collagenase

实验方案>

实验步骤

引用文献(0)>

清除