Anti-IkB Beta/NFKBIB Antibody (Clone#FDH-14)

Rabbit monoclonal antibody

说明书一键复制产品信息

筛选器： All WB IHC ICC/IF IP

BM4514

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

加入购物车立即购买

Western blot analysis of anti-NFKBIB antibody (BM4514). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human Jurkat whole cell lysates,
Lane 2: human Hela whole cell lysates,
Lane 3: human MCF-7 whole cell lysates,
Lane 4: human A549 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-NFKBIB antigen affinity purified monoclonal antibody (BM4514) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for NFKBIB at approximately 48 kDa. The expected band size for NFKBIB is at 38 kDa.
all(4)
Immunohistochemical analysis of paraffin-embedded human uterus, using IKB beta Antibody.
all(4)
all(4)
all(4)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-IkB Beta/NFKBIB Antibody (Clone#FDH-14)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

I kappa B beta; IkappaBbeta; IkB B; IkB beta; IKBB; NF kappa B inhibitor beta; NF kappa BIB; NFKBIB; TR interacting protein 9; TRIP 9; TRIP9

产品类型

Monoclonal

检验物种

human

应用范围

WB, IHC, ICC/IF, IP

基因名称

NFKBIB

克隆号

FDH-14

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human IKB beta

计算分子量

38 kDa

实际分子量

48 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

NF-kappa-B inhibitor beta, also known as IKBB or TRIP9, is a protein that in humans is encoded by the NFKBIB gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. This gene is mapped to 19q13.2. It has been found that in vivo, NFKBIB serves both to inhibit and to facilitate the inflammatory response. NFKBIB degradation releases NF-kappa-B dimers, which upregulate proinflammatory target genes such as TNF-alpha. Surprisingly, absence of NFKBIB results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide, even though activation of NF-kappa-B is normal.

Uniprot ID

Q15653

文献引用格式

IkB Beta/NFKBIB Antibody (Clone#FDH-14) (Boster Biological Technology, Wuhan, China. Catalog#BM4514)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

NF-kappa-B inhibitor beta

实验方案>

实验步骤

引用文献(0)>

清除