Anti-RAF1 (Phospho-S621) Antibody (Clone#IOF-18)

Rabbit Monoclonal antibody

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筛选器： All WB

BM4778

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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Western blot analysis of Phospho-Raf1 (S621) expression in (1) HeLa cell lysate treated with LP; (2) HeLa cell lysate.
all(3)
All lanes use the Antibody for 1 hour at room temperature.
all(3)
All lanes use the Antibody for 1 hour at room temperature.
all(3)

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产品简介>

产品名称

Anti-RAF1 (Phospho-S621) Antibody (Clone#IOF-18)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

c Raf; CRAF; NS5; Proto oncogene c RAF; RAF; Raf 1; RAF1

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

基因名称

RAF1

克隆号

IOF-18

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human Phospho-Raf1 (S621)

计算分子量

73 kDa

实际分子量

73 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme that in humans is encoded by the RAF1 gene. This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinasekinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Uniprot ID

P04049

文献引用格式

RAF1 (Phospho-S621) Antibody (Clone#IOF-18) (Boster Biological Technology, Wuhan, China. Catalog#BM4778)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

RAF proto-oncogene serine/threonine-protein kinase

实验方案>

实验步骤

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