Anti-NR1H3 Antibody (Clone#ABEB-14)
送常用试剂

Rabbit monoclonal antibody

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筛选器： All WB ICC/IF FCM

BM5134

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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Western blot analysis of anti-NR1H3 antibody (BM5134). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human Jurkat whole cell lysates,
Lane 2: human Hela whole cell lysates,
Lane 3: human HepG2 whole cell lysates,
Lane 4: human MCF-7 whole cell lysates,
Lane 5: rat liver tissue lysates,
Lane 6: rat lung tissue lysates,
Lane 7: mouse liver tissue lysates,
Lane 8: mouse lung tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-NR1H3 antigen affinity purified monoclonal antibody (BM5134) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for NR1H3 at approximately 45 kDa. The expected band size for NR1H3 is at 50 kDa.
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产品简介>

产品名称

Anti-NR1H3 Antibody (Clone#ABEB-14)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

Liver X receptor alpha; LXR a; LXRA; LXRα; NR1H3; Oxysterols receptor LXR alpha; RLD 1

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, ICC/IF, FCM

基因名称

NR1H3

克隆号

ABEB-14

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human LXR alpha

计算分子量

50 kDa

实际分子量

50 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

LXRA is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport. LXRs are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease. Furthermore, LXRs and their ligands are negative regulators of macrophage inflammatory gene expression. LXR is also found that as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis. The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake.

Uniprot ID

Q13133

文献引用格式

NR1H3 Antibody (Clone#ABEB-14) (Boster Biological Technology, Wuhan, China. Catalog#BM5134)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Oxysterols receptor LXR-alpha

实验方案>

实验步骤

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