产品名称
Anti-GADD153/DDIT3 Antibody (Clone#OTI4G2)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
CEBPZ; CHOP; CHOP 10; CHOP; GADD153; DDIT 3; DDIT3; GADD153
免疫原
Full length human recombinant protein of human DDIT3 (NP_004074) produced in E.coli.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
文献引用格式
GADD153/DDIT3 Antibody (Clone#OTI4G2) (Boster Biological Technology, Wuhan, China. Catalog#M00311-1)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
DNA-damage inducible transcript 3
蛋白名全称
DNA damage-inducible transcript 3 protein