Anti-CRK Antibody (Clone#24C53)

Rabbit monoclonal antibody

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筛选器： All WB ICC/IF IP FCM

M02533-3

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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Western blot analysis of CRKII expression in K562 cell lysate.
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IF analysis of CRK using anti-CRK antibody (BM4740) and anti-Beta Tubulin antibody (M02533-3).
CRK was detected in an immunocytochemical section of Hela cells. Cy3-conjugated Anti-mouse IgG Secondary Antibody (red)(Catalog#BA1031) and Dylight488-conjugated Anti-mouse IgG Secondary Antibody (green)(Catalog#BA1126) was used as secondary antibody.
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产品简介>

产品名称

Anti-CRK Antibody (Clone#24C53)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

Adapter molecule crk; CRK; CRKII; p38; Proto oncogene c Crk

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, ICC/IF, IP, FCM

基因名称

CRK

克隆号

24C53

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human CRKII

计算分子量

34 kDa

实际分子量

38 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

CRK, also known as p38 or CRKII, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The CRK protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Uniprot ID

P46108

文献引用格式

CRK Antibody (Clone#24C53) (Boster Biological Technology, Wuhan, China. Catalog#M02533-3)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

v-crk avian sarcoma virus CT10 oncogene homolog

蛋白名全称

Adapter molecule crk

实验方案>

实验步骤

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