产品名称
Anti-MKL1/MRTFA Antibody (Clone#OTI2B9)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
BSAC; KIAA1438; MAL; MKL/myocardin like protein 1; MKL1; MRTF A; MRTFA; MRTF-A
免疫原
Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1 (NP_065882) produced in E.coli.
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
文献引用格式
MKL1/MRTFA Antibody (Clone#OTI2B9) (Boster Biological Technology, Wuhan, China. Catalog#M32468-1)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
myocardin related transcription factor A
蛋白名全称
Myocardin-related transcription factor A