Anti-RANKL/TNFSF11 Antibody

Rabbit polyclonal antibody

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筛选器： All WB ELISA

PB1064

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of RANKL/TNFSF11 using anti-RANKL/TNFSF11 antibody (PB1064). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: rat brain tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-RANKL/TNFSF11 antigen affinity purified polyclonal antibody (PB1064) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for RANKL/TNFSF11 at approximately 35-40 kDa. The expected band size for RANKL/TNFSF11 is at 35 kDa.
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产品名称

Anti-RANKL/TNFSF11 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

CD254; hRANKL2; ODF; OPGL; OPTB2; Osteoprotegerin ligand; RANKL; sOdf; TNFSF11; TRANCE

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

WB, ELISA

基因名称

TNFSF11

宿主

Rabbit

抗体亚型

IgG

免疫原

E. coli-derived rat RANKL recombinant protein (Position: F141-D318). Rat RANKL shares 87.9% and 96.6% amino acid (aa) sequence identity with human and mouse RANKL, respectively.

计算分子量

35 kDa

实际分子量

35-40 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. It is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Uniprot ID

Q9ESE2

文献引用格式

RANKL/TNFSF11 Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB1064)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

tumor necrosis factor superfamily member 11

蛋白名全称

Tumor necrosis factor ligand superfamily member 11

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