Anti-Serotonin transporter/SLC6A4 Antibody

Rabbit polyclonal antibody

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筛选器： All WB

BA3706-2

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of Serotonin transporter/SLC6A4 using anti-Serotonin transporter/SLC6A4 antibody (BA3706-2). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: U87 whole cell lysates,
Lane 2: HELA whole cell lysates,
Lane 3: JURKAT whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-Serotonin transporter/SLC6A4 antigen affinity purified polyclonal antibody (BA3706-2) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for Serotonin transporter/SLC6A4 at approximately 70-90 kDa. The expected band size for Serotonin transporter/SLC6A4 is at 70 kDa.
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产品简介>

产品名称

Anti-Serotonin transporter/SLC6A4 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

5 HTT; 5 HTTLPR; 5HT transporter; 5HTT; hSERT; HTT; OCD1; serotonin transporter; SERT; SLC6A4

产品类型

Polyclonal

检验物种

human

应用范围

基因名称

SLC6A4

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A4.

计算分子量

70 kDa

实际分子量

70-90 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

SLC6A4(Solute carrier family 6, member 4), also known as SERT(serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.

Uniprot ID

P31645

文献引用格式

Serotonin transporter/SLC6A4 Antibody (Boster Biological Technology, Wuhan, China. Catalog#BA3706-2)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

solute carrier family 6(neurotransmitter transporter, serotonin), member 4

蛋白名全称

Sodium-dependent serotonin transporter

实验方案>

实验步骤

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