Anti-p63/TP63 Antibody (Clone#FCB-20)

Rabbit monoclonal antibody

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筛选器： All WB IHC ICC/IF FCM

BM4498

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of anti-p63/TP63 antibody (BM4498). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human RT4 whole cell lysates,
Lane 2: human Hacat whole cell lysates,
Lane 3: human A431 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-p63/TP63 antigen affinity purified monoclonal antibody (BM4498) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for p63/TP63 at approximately 77 kDa. The expected band size for p63/TP63 is at 63 kDa.
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody.
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Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody.
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Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast, using p63 Antibody.
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Immunofluorescent analysis of A431 cells, using p63 Antibody.
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产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-p63/TP63 Antibody (Clone#FCB-20)

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

AIS; B(p51A); B(p51B); CUSP; EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP63; TP73L; Tumor protein 63; tumor protein p63; Tumor protein p73 like

产品类型

Monoclonal

检验物种

human, mouse, rat

应用范围

WB, IHC, ICC/IF, FCM

基因名称

TP63

克隆号

FCB-20

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human p63

计算分子量

63 kDa

实际分子量

77 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Tumor protein p63 (TP63), also known as the p63 or TP73L is a protein that in humans is encoded by the TP63 gene. It is mapped to 3q28. TP63 is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. TP63 is an essential regulator of stem cell maintenance in stratified epithelial tissues. Tp63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.

Uniprot ID

Q9H3D4

文献引用格式

p63/TP63 Antibody (Clone#FCB-20) (Boster Biological Technology, Wuhan, China. Catalog#BM4498)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

Tumor protein 63

实验方案>

实验步骤

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