产品名称
Anti-TIMP2 Antibody (Clone#AADE-20)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
CSC 21K; Metalloproteinase inhibitor 2; TIMP 2; TIMP2; TIMP-2
免疫原
A synthesized peptide derived from human TIMP2
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
TIMP metallopeptidase inhibitor 2, a tissue inhibitor of metalloproteinases, also known as TIMP2, is a human gene, thought to be a metastasis suppressor. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
文献引用格式
TIMP2 Antibody (Clone#AADE-20) (Boster Biological Technology, Wuhan, China. Catalog#BM5024)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Metalloproteinase inhibitor 2
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| Flow Cytometry (FCM): | 1:20 |
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