产品名称
Anti-CHAT Antibody (Clone#ABBO-3)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
CHAT; CHOACTase; Choline acetylase; choline acetyltransferase; Choline O acetyltransferase; CMS1A; CMS1A2
应用范围
WB, IHC, ICC/IF, IP, FCM
免疫原
A synthesized peptide derived from human CHAT
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
Choline acetyltransferase (commonly abbreviated as°ChAT,but sometimes°CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans,the choline acetyltransferase enzyme is encoded by the°CHAT gene. This gene product is a characteristic feature of cholinergic neurons,and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene,and some of these variants have been shown to encode more than one isoform.
文献引用格式
CHAT Antibody (Clone#ABBO-3) (Boster Biological Technology, Wuhan, China. Catalog#BM5100)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Choline O-acetyltransferase
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| Immunohistochemistry (IHC): | 1:50-200 |
| Immunocytochemistry/Immunofluorescence (ICC/IF): | 1:50-200 |
| ImmunoPrecipitation (IP): | 1:50 |
| Flow Cytometry (FCM): | 1:50 |
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