Anti-ABCC2 Antibody (Clone#ABDD-1)

Rabbit monoclonal antibody

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筛选器： All WB ICC/IF FCM

BM5126

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Figure 1. Western blot analysis of ABCC2 using anti-ABCC2 antibody (BM5126). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human HepG2 whole cell lysates,
Lane 2: human A549 whole cell lysates,
Lane 3: human Caco-2 whole cell lysates,
Lane 4: human HUH-7 whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-ABCC2 antigen affinity purified polyclonal antibody (BM5126) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for ABCC2 at approximately 170-250 kDa. The expected band size for ABCC2 is at 174 kDa.
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产品简介>

产品名称

Anti-ABCC2 Antibody (Clone#ABDD-1)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

ABC30; ABCC2; CMOAT; CMOAT1; cMRP; DJS; KIAA1010; MRP2

产品类型

Monoclonal

检验物种

human

应用范围

WB, ICC/IF, FCM

基因名称

ABCC2

克隆号

ABDD-1

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human MRP2

计算分子量

174 kDa

实际分子量

170-250 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.

背景资料

Multidrug resistance-associated protein 2 (MRP2), also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 (ABCC2), is a protein that in humans is encoded by the ABCC2 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.

Uniprot ID

Q92887

文献引用格式

ABCC2 Antibody (Clone#ABDD-1) (Boster Biological Technology, Wuhan, China. Catalog#BM5126)

应用释义

WB- 蛋白质免疫印迹法,IHC- 免疫组织化学法,ICC/IF-免疫细胞荧光,ICC－免疫细胞化学,IHC-F- 冰冻切片免疫组化,FCM-流式细胞术,ELISA-酶联免疫吸附测定,IP-免疫沉淀法 ,IF-免疫组织荧光法,ChIP-染色质免疫沉淀法

基因名全称

Canalicular multispecific organic anion transporter 1

实验方案>

实验步骤

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