产品名称
Anti-BubR1/BUB1B Antibody (Clone#ABFG-2)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
Bub1A; BUB1B; BUB1beta; BubR1; hBUBR1; MAD3L; Protein SSK1; SSK1
免疫原
A synthesized peptide derived from human BubR1
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
文献引用格式
BubR1/BUB1B Antibody (Clone#ABFG-2) (Boster Biological Technology, Wuhan, China. Catalog#BM5149)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| Immunohistochemistry (IHC): | 1:50-200 |
| ImmunoPrecipitation (IP): | 1:30 |
| Flow Cytometry (FCM): | 1:50 |
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