产品名称
Anti-p70 S6K/RPS6KB1 Antibody (Clone#18R84)
规格/价格
50μl/1280 100μl/2180 150μl/2800
指标别称
p70 alpha; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K 1; p70 S6K alpha; p70 S6KA; p70(S6K); p70(S6K) alpha; p70S6K; P70S6K1; PS6K; Ribosomal protein S6 kinase I; RPS6KB1; S6K; S6K beta 1; S6K1; STK14A
应用范围
WB, IHC, ICC/IF, FCM
免疫原
A synthesized peptide derived from human P70 S6 Kinase alpha
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway. It plays a key role in cell growth and proliferation by regulating INS sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy (PMID:22684641). RPS6KB1 is a 70 kDa protein and has 5 isoforms with the calculated molecular mass of 51-59 kDa produced by alternative initiation.
文献引用格式
p70 S6K/RPS6KB1 Antibody (Clone#18R84) (Boster Biological Technology, Wuhan, China. Catalog#M01475-4)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Ribosomal protein S6 kinase beta-1
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| Immunohistochemistry (IHC): | 1:50-200 |
| Immunocytochemistry/Immunofluorescence (ICC/IF): | 1:50-200 |
| Flow Cytometry (FCM): | 1:200 |
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