Anti-BCL10 Antibody

Rabbit polyclonal antibody

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筛选器： All WB IHC

PB0555

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of anti-BCL10 antibody (PB0555). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: human Raji whole cell lysates,
Lane 2: human Jurkat whole cell lysates,
Lane 3: human MCF-7 whole cell lysates,
Lane 4: human Hela whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-BCL10 antigen affinity purified polyclonal antibody (PB0555) and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for BCL10 at approximately 28 kDa. The expected band size for BCL10 is at 26 kDa.
all(2)
IHC analysis of BCL10 using anti-BCL10 antibody (PB0555).
BCL10 was detected in a paraffin-embedded section of human lymph node carcinoma tissue. The tissue section was developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.
all(2)

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产品简介>

产品名称

Anti-BCL10 Antibody

规格/价格

50μl|1280 100μl|2180 150μl|2800

指标别称

B cell CLL/lymphoma 10; B cell lymphoma/leukemia 10; BCL10; c E10; CARD like apoptotic protein; CARMEN; cCARMEN; Cellular E10; Cellular homolog of vCARMEN; CIPER; CLAP; hCLAP; mE10

产品类型

Polyclonal

检验物种

human

应用范围

WB, IHC

基因名称

BCL10

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Bcl10, identical to the related rat and mouse sequences.

计算分子量

26 kDa

实际分子量

26 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

BCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue(MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain(CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are though to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are though to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Uniprot ID

O95999

文献引用格式

BCL10 Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB0555)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

B-cell CLL/lymphoma 10

蛋白名全称

B-cell lymphoma/leukemia 10

实验方案>

实验步骤

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