Anti-CIP2A Antibody

Rabbit polyclonal antibody

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筛选器： All WB

PB0754

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of CIP2A using anti-CIP2A antibody (PB0754). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: Mouse Testis tissue lysates,
Lane 2: HELA whole cell lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-CIP2A antigen affinity purified polyclonal antibody (PB0754) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for CIP2A at approximately 102 kDa. The expected band size for CIP2A is at 102 kDa.
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产品简介>

产品名称

Anti-CIP2A Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

Cancerous inhibitor of PP2A; CIP2A; KIAA1524; p90; p90 autoantigen; Protein CIP2A

产品类型

Polyclonal

检验物种

human, mouse, rat

应用范围

基因名称

CIP2A

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA1524 different from the related mouse sequence by three amino acids.

计算分子量

102 kDa

实际分子量

102 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

Protein CIP2A, also known as°Cancerous inhibitor of PP2A (CIP2A), is a protein that in humans is encoded by the KIAA1524 gene. CIP2A is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression of CIP2A promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

Uniprot ID

Q8TCG1

文献引用格式

CIP2A Antibody (Boster Biological Technology, Wuhan, China. Catalog#PB0754)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

KIAA1524

蛋白名全称

Protein CIP2A

实验方案>

实验步骤

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