Anti-MYD88 Antibody

Rabbit polyclonal antibody

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筛选器： All WB ELISA(Cap)

A00025-1

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of MYD88 using anti-MYD88 antibody (A00025-1). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
Lane 1: mouse spleen tissue lysates,
Lane 2: mouse testis tissue lysates,
Lane 3: rat spleen tissue lysates.
After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-MYD88 antigen affinity purified polyclonal antibody (A00025-1) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for MYD88 at approximately 33 kDa. The expected band size for MYD88 is at 33 kDa.
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产品简介>

产品名称

Anti-MYD88 Antibody

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

MYD88; MYD88D

产品类型

Polyclonal

检验物种

mouse, rat

应用范围

WB, ELISA(Cap)

基因名称

Myd88

宿主

Rabbit

抗体亚型

IgG

免疫原

E. coli-derived mouse MyD88 recombinant protein (Position: S12-D263).

计算分子量

33 kDa

实际分子量

33 kDa

成分

500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.

纯化方式

Immunogen affinity purified.

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.

Uniprot ID

P22366

RRID

AB_3080892

文献引用格式

MYD88 Antibody (Boster Biological Technology, Wuhan, China. Catalog#A00025-1)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

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