Anti-MYD88 Antibody (Clone#OTI1B4)

Mouse monoclonal antibody

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M00025-5

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期： 5-7天

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HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MYD88 antibody, and then analyzed by flow cytometry.
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Flow cytometric Analysis of Hela cells, using anti-MYD88 antibody, (Red), compared to a nonspecific negative control antibody, (Blue).
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Anti-MYD88 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYD88 .
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Flow cytometric Analysis of Jurkat cells, using anti-MYD88 antibody, (Red), compared to a nonspecific negative control antibody, (Blue).
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYD88 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYD88.
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产品简介>

产品名称

Anti-MYD88 Antibody (Clone#OTI1B4)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

MYD88; MYD88D

产品类型

Monoclonal

检验物种

human

应用范围

WB, ICC/IF, FCM

基因名称

MYD88

克隆号

OTI1B4

宿主

Mouse

抗体亚型

IgG2a

免疫原

Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.

计算分子量

33 kDa

实际分子量

33.1 kDa

成分

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

纯化方式

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

浓度

500 ug/ml

产品形态

Liquid

保存条件

Stable for 12 months from date of receipt. Store at -20°C as received.

背景资料

MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.

Uniprot ID

Q99836

文献引用格式

MYD88 Antibody (Clone#OTI1B4) (Boster Biological Technology, Wuhan, China. Catalog#M00025-5)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

基因名全称

MYD88 innate immune signal transduction adaptor

蛋白名全称

Myeloid differentiation primary response protein MyD88

实验方案>

实验步骤

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