Anti-MYD88 Antibody (Clone#FED-13)

Rabbit monoclonal antibody

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筛选器： All WB IHC ICC/IF FCM

BM4520

50μl ￥1280 100μl ￥2180 150μl ￥2800
货期：现货

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Western blot analysis of MyD88 expression in Raji cell lysate.
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Immunohistochemical analysis of paraffin-embedded human breast cancer, using MyD88 Antibody.
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Immunofluorescent analysis of A549 cells, using MyD88 Antibody.
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产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称

Anti-MYD88 Antibody (Clone#FED-13)

规格/价格

50μl/1280 100μl/2180 150μl/2800

指标别称

MYD88; MYD88D

产品类型

Monoclonal

检验物种

human

应用范围

WB, IHC, ICC/IF, FCM

基因名称

MYD88

克隆号

FED-13

宿主

Rabbit

抗体亚型

IgG

免疫原

A synthesized peptide derived from human MyD88 Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF- Kappa B and subsequent regulation of immune and inflammatory genes.

计算分子量

33 kDa

实际分子量

33 kDa

成分

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

纯化方式

Affinity-chromatography

浓度

500 ug/ml

产品形态

Liquid

保存条件

12 months from date of receipt，-20℃ as supplied.

背景资料

MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors(TLRs) and interleukin-1 receptors(IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Qverexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.

Uniprot ID

Q99836

文献引用格式

MYD88 Antibody (Clone#FED-13) (Boster Biological Technology, Wuhan, China. Catalog#BM4520)

应用释义

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

实验方案>

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