产品名称
Anti-CDC42 (Phospho-Ser71) Antibody (Clone#IBB-3)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
CDC42; CDC42Hs; G25K; G25K GTP binding protein
免疫原
A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71)
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt,-20℃ as supplied.
背景资料
Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
文献引用格式
CDC42 (Phospho-Ser71) Antibody (Clone#IBB-3) (Boster Biological Technology, Wuhan, China. Catalog#BM4794)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Cell division control protein 42 homolog
推荐稀释比
| Western blot (WB): | 1:500-2000 |