Anti-FGFR2 Antibody (Clone#AAAD-6)

50μl/1280 100μl/2180 150μl/2800

BEK; BFR 1; CD332; CEK3; CFD1; ECT1; FGFR 2; FGFR2; JWS; K SAM; KGFR; KSAM; TK14; TK25

Monoclonal

human, mouse, rat

WB, IP

FGFR2

AAAD-6

Rabbit

IgG

A synthesized peptide derived from human FGFR2

92 kDa

145 kDa

500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.

Affinity-chromatography

500 ug/ml

Liquid

12 months from date of receipt，-20℃ as supplied.

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

P21802  

FGFR2 Antibody (Clone#AAAD-6) (Boster Biological Technology, Wuhan, China. Catalog#BM4991)

WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;

Fibroblast growth factor receptor 2

Western blot (WB):	1:500-2000
ImmunoPrecipitation (IP):	1:20