产品名称
Anti-F2 Antibody (Clone#ACBD-6)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
Coagulation factor II; F2; Prothrombin; PT
免疫原
A synthesized peptide derived from human Prothrombin
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
保存条件
12 months from date of receipt，-20℃ as supplied.
背景资料
F2(Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al.(1987) assigned the gene for human prothrombin(F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by activating protein C.
文献引用格式
F2 Antibody (Clone#ACBD-6) (Boster Biological Technology, Wuhan, China. Catalog#BM5224)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
推荐稀释比
| Western blot (WB): | 1:500-2000 |
| ImmunoPrecipitation (IP): | 1:20 |
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