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Anti-HNF4A Antibody (Clone#OTI8B8)

Mouse monoclonal antibody

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筛选器: All WB

M00389-5

  • 50μl ¥1280 100μl ¥2180 150μl ¥2800
  • 货期: 5-7天
  • HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HNF4A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HNF4A.

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产品名称
Anti-HNF4A Antibody (Clone#OTI8B8)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
hepatocyte nuclear factor 4 alpha; FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14; HNF4A
产品类型
Monoclonal
检验物种
human, mouse, rat
应用范围
WB
基因名称
HNF4A
克隆号
OTI8B8
宿主
Mouse
抗体亚型
IgG2a
免疫原
Human recombinant protein fragment corresponding to amino acids 1-315 of human HNF4A(NP_849180) produced in E.coli.
计算分子量
53 kDa
成分
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
纯化方式
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度
500 ug/ml
产品形态
Liquid
保存条件
Stable for 12 months from date of receipt. Store at -20°C as received.
背景资料
Hepatocyte nuclear factor 4 alpha (HNF4A), also known as NR2A1, is a nuclear receptor that in humans is encoded by the HNF4A gene. It is mapped to 20q13.12. HNF4A is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene plays a role in development of the liver, kidney, and intestines. HNF4A is required for the PXR and CAR-mediated transcriptional activation of CYP3A4. This gene also plays a pivotal role in the expression and synthesis of SHBG, an important glycoprotein made primarily in the liver, which in addition to lowering insulin-resistance also serves in reducing levels of free Oestrogen as-well as prolonging the half-life of Testosterone.
Uniprot ID
P41235  
文献引用格式
HNF4A Antibody (Clone#OTI8B8) (Boster Biological Technology, Wuhan, China. Catalog#M00389-5)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
hepatocyte nuclear factor 4, alpha
蛋白名全称
Hepatocyte nuclear factor 4-alpha
推荐稀释比
Western blot (WB):1:2000

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    Anti-HNF4A Antibody (Clone#OTI8B8)

    筛选器: All WB

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